Antibiotic Resistance is a bigger problem worldwide

Antibiotic Resistance is a bigger problem worldwide.

The 12 deadly Superbugs are posing the greatest threat to the health of human being.

By Mahmood Hussain 11th September 2017 for and Baby First Pakistan as well for social media such as Facebook/babyfirstpk, Linkedin, Twitter and other social media.

In this regard WHO has raised their concern and published detail report. This was published at the end of February 2017. Which appears with the headline:

“The 12 deadly Superbugs are posing the threat to the health of human being”.

These are listed as the superbug, these deadly bacteria may affect us or our loved ones. We all need to know and should be aware the of these superbugs.

By the end of February 2017, World Health Organization officials and experts published the first list of its kind and in which they listed these highly deadly superbugs. The list issued by WHO contains 12 drug resistant bacteria, which is described by them as:

“The greatest threat to the health of human being.”

بارہ بیکٹیریا بے قابو ہوگئے،وقت ہاتھ سے نکل رہاہے، اقوام متحدہ

سُپر بگس پر قابو پانے کے لیے نئی اینٹی بایوٹکس جلد تیار کرنا ہوں گی

The WHO, authorities have asked the governments, researchers and Pharmaceuticals organization to think seriously of it. All the three-stake holder should collectively work to search for new antibiotic molecules or group to cope up with this dangerous and life-threatening situation.

The expert of public health has described superbug and its rise as a global threat. They describe these as “Ticking Time Bomb”.

WHO drawn a list for the first time on 27 February 2017 which contains 12 bacterial threats. They have “divided them into three categories and is term as critical, high and medium.”

The resistance to the antibiotic is growing. It is becoming very difficult for the physician to treat their patients. They are running out of choice to select the right and effective antibiotic, what to prescribe to the patient suffering from bacterial infection, they look forward to recover patient from the sickness.

The Daily Dawn leading English daily on 24th April 2017 published three reports on this topic and devoted approximately one and a half page highlighting this as a crisis. This is arising due to antibiotic resistance.

 “Antibiotic resistance which is posing the serious threat also in Pakistan.”

Due to the prevailing conditions, the chances of medical disaster are very much imminent. The antibiotic use has been seriously abused by the self-medication, result of word of mouth advice by friends, relatives and acquaintance. Antibiotic is also frequently prescribed by the physicians and doctors. This all has also been observed very common practice in SARRC region. If we look at Pakistan pharma market for more than two decades, the share of the antibiotic market is within 24-26% of the total pharma market as reported by IMS. Secondly antibiotic has leading market share in Pakistan, in term of volume as well as value wise sales. This reflects a large amount of antibiotic consumption.


Antibiotics are used to treat infection and it is also used to prevent infection especially to provide secondary cover in case of the patient suffering from viral infection. Antibiotic are medicines.

The infection is mostly due to bacteria in human being or animals. Resistance to the antibiotic is developed either by bacterial gene mutation or by excessive use of the antibiotic.  (If self-medication trend persists in SARRC region) or if the patient is not following recommended doses schedule and regimen of antibiotic as prescribed by the physician. It becomes very difficult or challenging task for the doctors to treat such sufferer.

Treating such cases of antibiotic resistance, this will lead to higher medical and treatment cost, longer stay in the hospital and even increase the mortality rate due to this problem.


In this regard and to deal with the grave situation, an overall need is to change the way antibiotic is prescribed and its usage. If scientist or researchers are lucky enough to find and develop new antibiotic molecules, but the problem of excessive usage and self-medication will lead to antibiotic resistance even with the newly invented molecules. To manage and handle this situation, we our-self should exercise great caution in case of self-medication and doctor behavior to prescribe antibiotics needs to be change, to avoid the development of resistance with the newly developed antibiotic.

Dire need is to reduce the chances of spread of infection, which can be translated into “Prevention is better than cure.” this can be achieved through following practices:

  • Regular hand washing.
  • Timely and proper vaccination
  • Drink clean and safe water.
  • Eat safe, healthy and hygienic food
  • Go far safe sex.
  • Regular physical activity
  • Avoid contact or don’t go closer to the patient suffering from an infection.

The antibiotic resistance is at the dangerous level around the globe.

The trend of new resistant strains is developed and rising globally This means the ability to treat common bacterial infection is at a bigger risk. This has been observed when treating infection with antibiotic are becoming difficult. in cases of such as pneumonia, septicemia, tuberculosis, meningitis, urinary tract infection, sexually transmitted disease such as gonorrhea, also chances of infection due to surgery, bone infection and more. Sometimes it is impossible to treat with antibiotic because it loses its potential. This trend of resistance is relatively more where antibiotic can be purchased without the prescription or due to self-medication for human and animals. This is also more common among the countries where standard prescription guidelines for antibiotic are not followed and these are over prescribed by the doctors or veterinarian as well due to self-medication,

Proper guidelines are to be followed and strictly restrict the antibiotic availability from the medical store. The antibiotic should be sold on prescription through proper prescription otherwise we will go back in the era of 2nd world war or before it when antibiotics were not invented and to treat infection were the nightmare and this lead to death even in epidemic form.

The use of antibiotic .is meant to fight against bacterial infection. Secondly, its function is to kills or stop the growth of bacteria. What has been observed now antibiotic are no more effective, the reason cited is due to the development of super bug or bacterial resistance strains.  This has led to the development of resistance to the antibiotic at an alarming level. The reason is well understood this is due to the very frequent use of antibiotics over the period of few decades especially in the Indo-Pakistan and in overall SARRC countries…

In the overall SARRC region, especially in Pakistan crisis of resistance to the antibiotic is a big nuisance, which is leading towards disaster to treat the bacterial the human being.

The purpose of use of antibiotic is to make human body able to fight against bacterial infection.

Now a day’s antibiotics are not effective because of the super bugs, which has developed resistance against pathogenic bacteria.  It is due to excessive use of antibiotic in more than the decade.

The facts stated in this regard are:

  • Development of resistance to an antibiotic is greater threat globally.
  • Resistance to the antibiotic can affect to any human being living across the world.
  • This bacterial resistance can be observed in all age group.
  • The resistance to the antibiotic is natural, the bacteria mutate itself to develop the resistant strain.
  • If antibiotic use in the shape of abuse or without laboratory culture of human being or animal, this may accelerate the bacterial resistance.
  • The Patient or sick person if is resistant to antibiotic than this will incur additional cost and longer stay in the hospital to manage and treat this patient. This may also increase the mortality.
  • Infection such as pneumonia, typhoid, tuberculosis, urinary tract, and gonorrhea, bone infection are becoming difficult to treat because its causative agents the bacteria are least sensitive to the antibiotic.

The WHO reports further and its states by inventing or creating the new molecule of antibiotic will not be enough, towards the genuine issue of bacterial resistance. This means we won’t be able to deal with this worldwide pandemic issue, we all need to work to promote the saying “Prevention is better than cure”.

We all need to devise two prong strategies to address the issue of global bacterial resistance

  1. Better way of prevention from bacterial infection to be followed
  2. Appropriate use of currently available antibiotic on humans and animals.
  3. When new research antibiotic will be available this should be rationally and judicially used.


The report further highlighted nearly 2.0 million citizens of the USA who have suffered from infection and bacterial strains found were resistant to available antibiotics.  Center for Disease Control (CDC) reports 23,000 annual deaths in the USA due to antibiotic resistant cases.

Now what to talk about annual death rate in our SARRC countries. This need to be given serious thought by all stake holders which especially include overall people, doctors and pharmacies or medical stores. Greater responsibility lie on health authorities.


Article is written by Mahmood Hussain for  ,Baby First Pakistan for social media such as website, facebook, Linkedin, twitter etc.

About Mahmood Hussain

Professional Experience More than 36 years work experience in Healthcare & Pharmaceutical sectorDirector & General Manager Baby First (Pvt.) Ltd Pakistan March 2011 – till to date I have been associated with Baby First (Pvt) Ltd for more than 5 years. It is advisory, community and social interaction medium for parents 16-38 years and babies 0-6 years.General Manager Aga Khan Health Service Pakistasn December 2005 – December 2007 (2 years 1 month)Based at Karachi Pakistan Worked as General Manager managing Karachi & Baluchistan Health care services of AKHSP which includes primary and secondary health care centers and diagnostic centers on all areas nearly 102 centers which include three leading hospitals in Karachi.General Manager Janssen Cilag (Johnson & Johnson) February 1998 – January 2005 (7 years)Education MBA, Marketing 1995 – 1996, Preston University MSc, Biochemistry 1970 – 1974, Karachi University

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